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Joint Bone Spine. 2007 Oct;74(5):495-6. Epub 2007 Jul 9.

Sweet's syndrome in Behçet's disease.

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Internal Medicine Department, Moulay Ismail Military Hospital, Meknes, Morocco.


Few cases of Sweet's syndrome have been reported in patients with Behçet's disease.


A 47-year-old woman with five year history of oral and genital ulcers that had not been investigated previously was admitted for an eruption of tender, erythematous, vesicle-like papules over the face, neck, palms, and legs. She reported polyarthralgia and weight loss of 6 kg over the previous month. At admission, she had a fever of 38.5 degrees C and conjunctivitis. Joint tenderness to mobilization without evidence of synovitis was noted. Laboratory tests showed inflammation and leukocytosis (12.5x10(9)/L) with 74% neutrophils. The skin biopsy was typical for Sweet's syndrome, and the pathergy test was positive. Glucocorticoid therapy 40 mg/day and colchicine were effective in alleviating the manifestations.


Overlap exists between the clinical manifestations of Sweet's syndrome and Behçet's disease. Data from the literature suggest that Behçet's disease may be among the conditions that underlie Sweet's syndrome.

[Indexed for MEDLINE]

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