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Bioorg Med Chem Lett. 2007 Nov 15;17(22):6290-4. Epub 2007 Sep 7.

Discovery of 2,4,6-trisubstituted N-arylsulfonyl piperidines as gamma-secretase inhibitors.

Author information

1
Department of Chemical Research, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. hongmei.li@spcorp.cpm

Abstract

Development of cis-2,4,6-trisubstituted piperidine N-arylsulfonamides as gamma-secretase inhibitors for the potential treatment of Alzheimer's disease (AD) is reported.

PMID:
17890085
DOI:
10.1016/j.bmcl.2007.09.006
[Indexed for MEDLINE]

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