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Bioorg Med Chem Lett. 2007 Nov 15;17(22):6274-9. Epub 2007 Sep 7.

Rynaxypyr: a new insecticidal anthranilic diamide that acts as a potent and selective ryanodine receptor activator.

Author information

  • 1DuPont Crop Protection, Stine-Haskell Research Center, 1094 Elkton Road, Newark, DE 19711, USA. george.p.lahm@usa.dupont.com

Abstract

Rynaxypyr is a highly potent and selective activator of insect ryanodine receptors with exceptional activity on a broad range of Lepidoptera. A strong correlation between insecticidal activity and ryanodine receptor activation is observed along with selective activity against insect over mammalian receptors. The synthesis and biological results are presented.

PMID:
17884492
DOI:
10.1016/j.bmcl.2007.09.012
[PubMed - indexed for MEDLINE]

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