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Headache. 2007 Sep;47(8):1210-2.

Familial hemiplegic migraine: permanent attack-related neurologic deficits.

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Mayo Clinic, Scottsdale-Neurology, Scottsdale, AZ 85259, USA.


Hemiplegic migraine (HM) is characterized by motor weakness and at least one other aura symptom or sign that is fully reversible within 24 hours. While prolonged neurological impairment lasting weeks has been observed, persistent attack-related neurological deficits have not been described. This case illustrates the potential for permanent neurological deficits to occur as a sequelae of HM in the absence of infarction, and highlights potentially important pathophysiological and treatment implications.

[Indexed for MEDLINE]

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