Format

Send to

Choose Destination
J Clin Apher. 2007;22(5):295-8.

Plasmapheresis for hemolytic crisis and impending acute liver failure in Wilson disease.

Author information

1
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

Abstract

Wilsonian crisis is fatal unless copper removal is initiated early and liver transplantation is performed for patients that fulfill criteria for a poor outcome. We report a patient presenting with severe hemolysis and impending acute liver failure that made a rapid recovery with prompt initiation of plasmapheresis and chelation therapy. Rapid copper removal by plasmapheresis alleviated hemolysis and liver injury. A review of the literature was performed examining the use of plasmapheresis and albumin dialysis with continuous veno-venous hemodialysis or molecular adsorbents and recirculating system.

PMID:
17880018
DOI:
10.1002/jca.20140
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center