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J Am Vet Med Assoc. 1991 Sep 1;199(5):591-4.

Azathioprine for treatment of immune-mediated thrombocytopenia in two horses.

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Department of Clinical Studies, George D. Widener Hospital, New Balton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.


Azathioprine, a thiopurine antimetabolite used in the treatment of immune-mediated thrombocytopenia in human beings and dogs, was used in 2 cases of immune-mediated thrombocytopenia in horses that failed to respond to corticosteroid therapy alone. Platelet counts were increased to acceptable values in both horses. One horse returned to a successful racing career, and the other was euthanatized after developing renal disease and mild laminitis.

[Indexed for MEDLINE]

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