Format

Send to

Choose Destination
Best Pract Res Clin Rheumatol. 2007 Oct;21(5):871-83.

Mortality in established rheumatoid arthritis.

Author information

1
Rotherham General Hospital, South Yorkshire, UK.

Abstract

Rheumatoid arthritis (RA) is associated with reduced life expectancy. Whether the development of RA initiates this process of premature ageing or is part of it is not clear. The excess mortality is apparent within the first few years of disease and increases with RA disease duration. Most of the excess deaths are attributable to infection, cardiovascular disease (in particular coronary heart disease) and respiratory disease. Deaths due to lung cancer and non-Hodgkin's lymphoma, but not other cancers, are also increased. There is some evidence that effective disease-modifying therapy can improve survival but, overall, survival in RA patients has not improved to the same degree as in the general population over recent decades.

PMID:
17870033
DOI:
10.1016/j.berh.2007.05.003
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center