Send to

Choose Destination
Philos Trans A Math Phys Eng Sci. 2007 Dec 15;365(1861):3033-45.

Brain architecture: a design for natural computation.

Author information

School of Computing Science, University of Newcastle, Claremont Tower, Newcastle upon Tyne NE1 7RU, UK.


Fifty years ago, John von Neumann compared the architecture of the brain with that of the computers he invented and which are still in use today. In those days, the organization of computers was based on concepts of brain organization. Here, we give an update on current results on the global organization of neural systems. For neural systems, we outline how the spatial and topological architecture of neuronal and cortical networks facilitates robustness against failures, fast processing and balanced network activation. Finally, we discuss mechanisms of self-organization for such architectures. After all, the organization of the brain might again inspire computer architecture.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center