Long-term use of daptomycin for MRSA osteomyelitis and joint infection

Scand J Infect Dis. 2008;40(2):183-6. doi: 10.1080/00365540701633038.

Abstract

This case describes almost continual daptomycin use for approximately 18 months in a patient with osteomyelitis caused by methicillin-resistant Staphylococcus aureus. The case is notable for only a brief episode of myalgia-associated creatine kinase elevations, which quickly resolved. Daptomycin demonstrated efficacy against this strain, which was tolerant to other antibiotics.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents / administration & dosage*
  • Arthritis, Infectious / drug therapy*
  • Daptomycin / administration & dosage*
  • Drug Administration Schedule
  • Humans
  • Male
  • Methicillin Resistance / drug effects*
  • Microbial Sensitivity Tests
  • Osteomyelitis / drug therapy*
  • Osteomyelitis / microbiology
  • Staphylococcal Infections / drug therapy*
  • Staphylococcus aureus / drug effects

Substances

  • Anti-Bacterial Agents
  • Daptomycin