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J Minim Invasive Gynecol. 2007 Sep-Oct;14(5):616-21.

Mid-term outcome of magnetic resonance-guided focused ultrasound surgery for uterine myomas: from six to twelve months after volume reduction.

Author information

1
Department of Gynecology, Shinsuma Hospital, Kobe, Hyogo, Japan. funakikaoru@ybb.ne.jp

Abstract

STUDY OBJECTIVE:

To clarify the volume change ratio of uterine myomas treated with magnetic resonance-guided focused ultrasound surgery (MRgFUS), in relation to the signal intensity of T(2)-weighted magnetic resonance (MR) images.

DESIGN:

Prospective study (Canadian Task Force classification II-3).

SETTING:

Department of Gynecology, Shinsuma General Hospital, Kobe, Japan.

PATIENTS:

Forty-eight myomas in 35 patients were followed up with MR images 6 months after MRgFUS, and 23 myomas in 17 patients were followed up 12 months after MRgFUS. Before treatment, the myomas were classified into 3 types on the basis of the signal intensity of T(2)-weighted MR images as follows: Type 1, low intensity; type 2, intermediate intensity; type 3, high intensity.

INTERVENTIONS:

Thermal ablation therapy was performed with an MRgFUS system (ExAblate 2000).

MEASUREMENTS AND MAIN RESULTS:

MRgFUS produced a greater volume reduction in type 1 and type 2 myomas than in type 3 myomas. Nonperfused areas always diminished in the period after MRgFUS; however, the volume change was affected by the volume change ratio of perfused areas inside the treated myomas.

CONCLUSION:

At present, type 3 myomas should be exempted from the application of MRgFUS, because the nonperfused ratio immediately after the procedure was small compared with that in type 1 and type 2 myomas, and the subsequent volume change was unfavorable.

PMID:
17848324
DOI:
10.1016/j.jmig.2007.04.009
[Indexed for MEDLINE]
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