Abstract
The complete characterization of two compounds obtained from the acetone extract of Populus tremula knotwood has been was achieved using LC-DAD-MS, MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixture of the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showed the capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trap peroxyl radicals, as determined by a chemiluminescence method. These new phenyl disaccharides also showed a significant ORAC (oxygen radical absorbance capacity) value, i.e. 11.7 microM TE (Trolox Equivalents).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antioxidants / pharmacology*
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Chromatography, Gas
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Chromatography, High Pressure Liquid
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Disaccharides / chemistry*
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Disaccharides / pharmacology
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Free Radical Scavengers / chemistry
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Lipid Peroxidation / drug effects
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Mass Spectrometry
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Peroxides / chemistry
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Phenols / chemistry*
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Phenols / pharmacology
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Plant Extracts / chemistry*
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Plant Extracts / pharmacology
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Populus / chemistry*
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Spectrophotometry, Ultraviolet
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Superoxides / chemistry
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Trees / chemistry
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Wood*
Substances
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Antioxidants
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Disaccharides
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Free Radical Scavengers
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Peroxides
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Phenols
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Plant Extracts
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Superoxides
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perhydroxyl radical