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J Bacteriol. 2007 Dec;189(24):9135-9. Epub 2007 Sep 7.

The pinholin of lambdoid phage 21: control of lysis by membrane depolarization.

Author information

1
Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, TX 77843-2128, USA.

Abstract

The phage 21 holin, S(21), forms small membrane holes that depolarize the membrane and is designated as a pinholin, as opposed to large-hole-forming holins, like S(lambda). Pinholins require secreted SAR endolysins, a pairing that may represent an intermediate in the evolution of canonical holin-endolysin systems.

PMID:
17827300
PMCID:
PMC2168629
DOI:
10.1128/JB.00847-07
[Indexed for MEDLINE]
Free PMC Article
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