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Cell. 2007 Sep 7;130(5):769-74.

Molecular understanding and modern application of traditional medicines: triumphs and trials.

Author information

1
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511, USA.

Abstract

Traditional medicines provide fertile ground for modern drug development, but first they must pass along a pathway of discovery, isolation, and mechanistic studies before eventual deployment in the clinic. Here, we highlight the challenges along this route, focusing on the compounds artemisinin, triptolide, celastrol, capsaicin, and curcumin.

PMID:
17803898
PMCID:
PMC2507744
DOI:
10.1016/j.cell.2007.08.021
[Indexed for MEDLINE]
Free PMC Article

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