Rapid sequence induction and intubation with 1 mg/kg rocuronium bromide in cesarean section, comparison with suxamethonium

Saudi Med J. 2007 Sep;28(9):1393-6.

Abstract

Objective: To demonstrate that Rocuronium Bromide can be used for rapid sequence induction in emergency conditions.

Methods: Our study was performed between December 2005 and May 2006 in Jordan University Hospital, Jordan. We studied the efficacy and intubating conditions after administrating of Rocuronium Bromide 1 mg/kg at 60 second in group of 60 pregnant women undergoing elective or emergency cesarean section and compared the results with those obtained after giving Suxamethonium 1 mg/kg at 60 seconds in a group of patients similar to the Rocuronium group.

Results: Intubating conditions after 1 mg /kg of Rocuronium Bromide were found to be acceptable (good and excellent) in 95% of patients and were similar to the Suxamethonium group (97%). The endotracheal tube could be passed through the vocal cards of all patients enrolled in the study.

Conclusion: Rocuronium Bromide 1 mg/kg can be safely used for rapid sequence induction in cesarean section and the intubating conditions are similar to those of Suxamethonium.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Androstanols / administration & dosage*
  • Anesthesia, Obstetrical / methods*
  • Anesthetics, Intravenous / administration & dosage
  • Cesarean Section*
  • Female
  • Humans
  • Intubation, Intratracheal*
  • Neuromuscular Nondepolarizing Agents / administration & dosage*
  • Pregnancy
  • Rocuronium
  • Succinylcholine
  • Thiopental / administration & dosage

Substances

  • Androstanols
  • Anesthetics, Intravenous
  • Neuromuscular Nondepolarizing Agents
  • Succinylcholine
  • Thiopental
  • Rocuronium