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Maturitas. 2007 Oct 20;58(2):150-5. Epub 2007 Sep 4.

Prevalence of metabolic syndrome during menopausal transition Tehranian women: Tehran Lipid and Glucose Study (TLGS).

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1
Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. s.samavatian@gmail.com

Abstract

OBJECTIVE:

This study was conducted to assess the prevalence of metabolic syndrome (MetS) in Tehranian women during menopausal transition.

DESIGN:

In this cross sectional study 2182 subjects, pre-menopausal (pre-M) n=537, menopausal (M) n=311 and post-menopausal (post-M) n=1334 were selected from 15005 participants of the TLGS and assessed for MetS risk factors. All MetS components were evaluated following age adjustment according to the ATPIII criteria.

RESULTS:

The mean ages of post-M, M and pre-M women were 61.0+/-4.3, 53.0+/-4.0 and 47.0+/-1.9 years, respectively. The prevalence of MetS in subjects was 63% (53%, 54% and 69%) in pre-M, M and post-M women respectively. HDL-c levels was significantly higher in post-M women in comparison to pre-M women (p<0.001). TG levels, FPG and waist circumference was significantly higher in post-M women in comparison to pre-M women (p<0.05). The most frequent markers of MetS were low HDL-c and high diastolic blood pressure in post-M women.

CONCLUSION:

It is concluded that the frequency of MetS is significantly higher in post-M women as compared to pre-M women; low HDL-c and high diastolic blood pressure is the most frequent feature in comparison to other factors.

PMID:
17768019
DOI:
10.1016/j.maturitas.2007.07.002
[Indexed for MEDLINE]
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