Format

Send to

Choose Destination
Mol Biochem Parasitol. 2007 Dec;156(2):93-101. Epub 2007 Jul 19.

Post-transcriptional regulation of gene expression in trypanosomes and leishmanias.

Author information

1
Zentrum für Molekualre Biologie der Universität Heidelberg, Im Neuenheimer Feld 282, D69120 Heidelberg, Germany. cclayton@zmbh.uni-heidelberg.de

Abstract

Gene expression in Kinetoplastids is very unusual in that the open reading frames are arranged in long polycistronic arrays, monocistronic mRNAs being created by post-transcriptional processing. Thus the regulation of gene expression is post-transcriptional. We here discuss recent results concerning the enzymes required for mRNA degradation, and components of the translation initiation machinery, and how both are regulated.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center