Format

Send to

Choose Destination
Trends Endocrinol Metab. 2007 Oct;18(8):308-13. Epub 2007 Aug 30.

It's all about sex: gender, lung development and lung disease.

Author information

1
National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

Abstract

Accumulating evidence suggests that gender affects the incidence, susceptibility and severity of several lung diseases. Gender also influences lung development and physiology. Data from both human and animal studies indicate that sex hormones might contribute to disease pathogenesis or serve as protective factors, depending on the disease involved. In this review, the influence of gender and sex hormones on lung development and pathology will be discussed, with specific emphasis on pulmonary fibrosis, asthma and cancer.

PMID:
17764971
PMCID:
PMC2391086
DOI:
10.1016/j.tem.2007.08.003
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center