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Nihon Kokyuki Gakkai Zasshi. 2007 Aug;45(8):598-603.

[Resected pulmonary sarcoidosis after corticosteroid treatment still showing pathological granulomatous inflammation].

[Article in Japanese]

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Third Department of Internal Medicine, National Defense Medical College.


It is not well understood what kind of histologic resolution is obtained with corticosteroid medication in sarcoidosis, or how we are able to judge cure in that disease. We examined the cases of sarcoidosis who were under steroid medication and received lobectomy and lymphadenectomy for combined lung cancer. Steroid treatment had been introduced for the relief of visual disturbance, not for the pulmonary lesion. Administration of corticosteroid improves clinical, laboratory, bronchoalveolar lavage and radiological findings, but it is difficult to make histological granulomatous inflammation completely disappear. Improvement of radiological and clinical problems in sarcoidosis is not the same as complete cure in patients with steroid-treated sarcoidosis.

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