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Spine (Phila Pa 1976). 2007 Sep 1;32(19):E544-50.

Intervertebral disc degeneration reduces vertebral motion responses.

Author information

1
Department of Kinesiology, Biomechanics Laboratory, Exercise and Sport Science Research Institute, Arizona State University, Tempe, AZ, USA. christopher.colloca@asu.edu

Abstract

STUDY DESIGN:

A prospective in vivo experimental animal study.

OBJECTIVE:

To determine the effects of disc degeneration and variable pulse duration mechanical excitation on dorsoventral lumbar kinematic responses.

SUMMARY OF BACKGROUND DATA:

In vitro and in vivo biomechanical studies have examined spine kinematics during posteroanterior loading mimicking spinal manipulation therapy (SMT), but few (if any) studies have quantified SMT loading-induced spinal motion responses in the degenerated intervertebral disc.

METHODS:

Fifteen sheep underwent a survival surgical procedure resulting in chronic disc degeneration of the L1-L2 disc. Ten age- and weight-matched animals served as controls. Uniform pulse dorsoventral mechanical forces (80 N) were applied to the L3 spinous processes using 10-, 100-, and 200-ms duration pulses mimicking SMT. L3 displacement and L2-L1 acceleration in the control group were compared with the degenerated disc group.

RESULTS:

Dorsoventral displacements increased significantly (fivefold, P < 0.001) with increasing mechanical excitation pulse duration (control and degenerated disc groups). Displacements and L2-L1 acceleration transfer were significantly reduced (approximately 19% and approximately 50%, respectively) in the degenerated disc group compared with control (100- and 200-ms pulse duration protocols, P < 0.01).

CONCLUSION:

Dorsoventral vertebral motions are dependent on mechanical excitation pulse duration and are significantly reduced in animals with degenerated discs.

PMID:
17762796
DOI:
10.1097/BRS.0b013e318145ac39
[Indexed for MEDLINE]

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