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Trends Biochem Sci. 1991 Nov;16(11):417-22.

Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization.

Author information

1
Howard Hughes Research Laboratory, Carnegie Institution of Washington, Baltimore, MD 21210.

Abstract

Many eukaryotic transcription factors contain domains that mediate the formation of homo- and heterodimers. The widespread occurrence of such domains suggests that they are important to the genetic regulatory apparatus. In this review we explore the contributions that heterotypic dimerization may make to the generation of regulatory diversity.

PMID:
1776171
DOI:
10.1016/0968-0004(91)90167-t
[Indexed for MEDLINE]

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