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Rev Infect Dis. 1991 Nov-Dec;13(6):1151-62.

Hemolysis and infection: categories and mechanisms of their interrelationship.

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  • 1Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30303.


Different cause-and-effect relationships between hemolytic and infectious processes are categorized in a clinically useful manner as follows: infections causing hemolysis by invasion of red blood cells (RBCs), by hemolysins, or by immune mechanisms; oxidative damage to RBCs during infections; hemolysis secondary to infection-induced pathologic processes; hemolytic effects of antimicrobial therapy; and predisposition of an individual to infection caused by an underlying hemolytic disorder or therapy for that disorder. The mechanisms of these interrelationships are discussed in detail.

[PubMed - indexed for MEDLINE]
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