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Br J Neurosurg. 1991;5(6):643-6.

Brain tumours and the occurrence of severe invasive basal cell carcinoma in first degree relatives with Gorlin syndrome.

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1
CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Manchester, UK.

Abstract

We describe the occurrence of a medulloblastoma and an astrocytoma in successive generations of a family with the Gorlin syndrome. The appearance of thousands of invasive basal cell carcinomata after craniospinal irradiation led to the death of one patient from intracranial involvement.

PMID:
1772613
[Indexed for MEDLINE]
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