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Stat Med. 2008 Mar 30;27(7):990-1007.

Estimating complete prevalence of cancers diagnosed in childhood.

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National Center for Epidemiology, Surveillance and Health Promotion, Department of Cancer Epidemiology, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.


A method of estimating the complete prevalence of cancers diagnosed in childhood called CHILDPREV (CHILDhood PREValence), is presented. It is a semi-parametric method based on cancer registry data and on the completeness index method. It allows estimating prevalence even when no observation is available (typically older patients alive at the prevalence date may have been diagnosed with cancer before the introduction of the registry). The method was validated on Connecticut Tumor Registry data, which has 62 years of follow-up and provides complete prevalence, and compared with the fully parametric PIAMOD method. Results of complete childhood prevalence estimates based on SEER-9 cancer registries data for acute lymphocytic leukemia and all cancer sites combined are presented.

[Indexed for MEDLINE]

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