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Acta Neurol Scand. 1991 Oct;84(4):326-33.

Vibratory and thermal thresholds in diabetics with and without clinical neuropathy.

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Gentofte Hospital, Department of Neurology, Aalborg Hospital, Copenhagen, Denmark.

Erratum in

  • Acta Neurol Scand 1992 Feb;85(2):159-60.


Vibration and thermal detection threshold and heat pain threshold were determined in 34 diabetics scrutinized for clinical neuropathy using a standardized questionnaire and examination form. On the basis of the clinical grading patients were classified as having either no neuropathy or a neuropathy of increasing severity. As expected thermal and vibratory detection threshold increased with increasing severity of neuropathy. Comparison between diabetics without symptoms and signs of neuropathy and a corresponding non-diabetic control group showed that a warm sensibility index (WSI = the range in which non-noxious heat is perceived) was significantly lower on feet in diabetics than in their matched non-diabetic controls. The findings show that quantitative assessment of thermal sensitivity may be of value to detect early small nerve fiber dysfunction even in patients without symptoms or signs of a clinical neuropathy.

[Indexed for MEDLINE]

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