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Psychiatr Clin North Am. 2007 Sep;30(3):453-79.

Reaching for wellness in schizophrenia.

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Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA. <>


Coronary heart disease (CHD) is a major cause of mortality in people who have schizophrenia, and it is caused by many factors relating to lifestyle choices, antipsychotic treatment, and other medical comorbidities. This article focuses on modifiable risk factors such as cigarette smoking, diabetes, hyperlipidemia, hypertension, and the metabolic syndrome, all of which occur more frequently in patients who have schizophrenia than in the general population. Although treatment of risk factors for CHD is still far from ideal, all attempts should be made to strive for wellness to improve patients' long-term outcomes.

[Indexed for MEDLINE]

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