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Gynecol Obstet Fertil. 2007 Sep;35(9):832-41. Epub 2007 Aug 24.

[Diethylstilbestrol exposure in utero. Polemics about metroplasty. The cons].

[Article in French]

Author information

1
Service de gynécologie-obstétrique, unité de médecine de la reproduction, hôpital Saint-Vincent-de-Paul, GHU Cochin-Saint-Vincent-de-Paul, 82, avenue Denfert-Rochereau, 75014 Paris, France. s.epelboin@svp.aphp.fr

Abstract

Uterine malformations in DES-exposed women are not the only aetiologies for infertility, miscarriages, and other problems in their reproductive life. A global screening of fertility factors of the couple may, for instance, show in them vascular uterine abnormalities which reduce their reproductive potential. Furthermore, these abnormalities are not always predictive of losses of pregnancy, and many exposed women with patent uterine abnormalities can carry a pregnancy to term. Metroplasty for uterine enlargement is a surgical procedure suggested for restoring the size and shape of the uterine cavity. There are no comparative studies for assessing efficacy and safety of metroplasty. Therefore, metroplasty should not be performed routinely, but should only be considered after the couple has undergone a full fertility workup, and the best possible level of fertility has been achieved.

PMID:
17719825
DOI:
10.1016/j.gyobfe.2007.07.025
[Indexed for MEDLINE]

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