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Cell. 2007 Aug 24;130(4):597-600.

Living with p53, dying of p53.

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1
Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot 76100, Israel.

Abstract

The p53 tumor suppressor protein acts as a major defense against cancer. Among its most distinctive features is the ability to elicit both apoptotic death and cell cycle arrest. In this issue of Cell, Das et al. (2007) and Tanaka et al. (2007) provide new insights into the mechanisms that dictate the life and death decisions of p53.

PMID:
17719538
DOI:
10.1016/j.cell.2007.08.005
[Indexed for MEDLINE]
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