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J Am Acad Dermatol. 2007 Dec;57(6):1019-20. Epub 2007 Aug 23.

An in vitro study comparing temperatures of over-the-counter wart preparations with liquid nitrogen.

Author information

1
University of Toledo College of Medicine, Toledo, Ohio 43560, USA. cgbakb@aol.com

Abstract

BACKGROUND:

Over-the-counter (OTC) wart-freezing therapies have appeared on the market claiming that they reproduce in-office cryotherapy.

OBJECTIVE:

We sought to determine whether these OTC home wart removal products are as cold as liquid nitrogen.

METHODS:

The coldness obtained by 3 representative commercial wart products, and liquid nitrogen, was assessed using a thermometer calibrated from -100 degrees C to 50 degrees C. Temperatures of the commercial wart products used were measured and compared with those obtained with liquid nitrogen.

RESULTS:

None of the OTC coolants were as cold as liquid nitrogen, and they did not lower temperature as quickly as liquid nitrogen.

LIMITATIONS:

This study did not evaluate the clinical efficacy of any of the agents studied.

CONCLUSIONS:

Despite advertising messages, OTC refrigerants do not achieve freezing equivalent to liquid nitrogen.

PMID:
17719128
DOI:
10.1016/j.jaad.2007.06.037
[Indexed for MEDLINE]

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