Human immunodeficiency virus type 1 (HIV-1) plasma load discrepancies between the Roche COBAS AMPLICOR HIV-1 MONITOR Version 1.5 and the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 assays

F Damond; B Roquebert; A Bénard; G Collin; M Miceli; P Yéni; F Brun-Vezinet; D Descamps

doi:10.1128/JCM.00973-07

Human immunodeficiency virus type 1 (HIV-1) plasma load discrepancies between the Roche COBAS AMPLICOR HIV-1 MONITOR Version 1.5 and the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 assays

J Clin Microbiol. 2007 Oct;45(10):3436-8. doi: 10.1128/JCM.00973-07. Epub 2007 Aug 22.

Authors

F Damond¹, B Roquebert, A Bénard, G Collin, M Miceli, P Yéni, F Brun-Vezinet, D Descamps

Affiliation

¹ Laboratoire de Virologie, Hôpital Bichat Claude Bernard, 75018 Paris, France. florence.damond@bch.aphp.fr

Abstract

We compared plasma viral load values obtained with COBAS AMPLICOR human immunodeficiency virus type 1 (HIV-1) MONITOR version 1.5 and with COBAS TaqMan HIV-1 assays. Mean values were 4.2 and 2.9 log(10) copies/ml, respectively, showing the lack of agreement between the two assays.

MeSH terms

HIV-1 / isolation & purification*
Humans
Polymerase Chain Reaction / methods*
RNA, Viral / blood*
Viral Load / methods*

Substances

RNA, Viral