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FEMS Microbiol Lett. 2007 Oct;275(2):191-8. Epub 2007 Aug 22.

In vivo colonization profile study of Bordetella bronchiseptica in the nasal cavity.

Author information

1
Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

Abstract

Bordetella bronchiseptica chronically infects a wide range of mammals, and resides primarily in the nasal cavity of the infected host. Multiple virulence factors of Bordetella species have been studied in the context of lower respiratory tract infections, but relatively less is known about the bacterial life cycle in the nasal cavity. Evidences were discovered for Bvg intermediate (Bvg(i)) phase expression in vivo and that the major adhesin filamentous hemagglutinin plays a major role in the colonization of B. bronchiseptica in the unciliated olfactory epithelia of the nasal cavity.

PMID:
17714485
PMCID:
PMC2121150
DOI:
10.1111/j.1574-6968.2007.00852.x
[Indexed for MEDLINE]
Free PMC Article

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