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Expert Rev Proteomics. 2007 Aug;4(4):565-72.

Nanobiotechnology: quantum dots in bioimaging.

Author information

1
Graduate School of Pharmaceutical Sciences, University of Tokushima, Shomachi, Tokushima, Japan. yl7173@gmail.com

Abstract

Many biological systems, including protein complexes, are natural nanostructures. To better understand these structures and to monitor them in real time, it is becoming increasingly important to develop nanometer-scale signaling markers. Single-molecule methods will play a major role in elucidating the role of all proteins and their mutual interactions in a given organism. Fluorescent semiconductor nanocrystals, known as quantum dots, have several advantages of optical and chemical features over the traditional fluorescent labels. These features make them desirable for long-term stability and simultaneous detection of multiple signals. Here, we review current approaches to developing a biological application for quantum dots.

PMID:
17705713
DOI:
10.1586/14789450.4.4.565
[Indexed for MEDLINE]
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