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Nat Protoc. 2007;2(8):1884-7.

Synthesis of the functionalizable methionine surrogate azidohomoalanine using Boc-homoserine as precursor.

Author information

1
Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91106, USA. ajlink@princeton.edu

Abstract

This protocol describes a synthetic route to the non-canonical amino acid azidohomoalanine (AHA) using protected homoserine as a starting material. An alternative route to AHA is presented in a companion paper. This synthesis can be completed in 5 days.

PMID:
17703199
DOI:
10.1038/nprot.2007.269
[Indexed for MEDLINE]

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