Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin Vaccine Immunol. 2007 Oct;14(10):1377-80. Epub 2007 Aug 15.

Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study.

Author information

  • 1Laboratory of Vaccine-Preventable Diseases, National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

Abstract

We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.

PMID:
17699831
PMCID:
PMC2168111
DOI:
10.1128/CVI.00175-07
[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center