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Neuropsychol Rev. 2007 Sep;17(3):317-36. Epub 2007 Aug 10.

The neuropsychology of amphetamine and opiate dependence: implications for treatment.

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1
School of Clinical Medicine, Department of Psychiatry, University of Cambridge, Brain Mapping Unit, Box 255, Addenbrooke's Hospital, Cambridge, UK. ke220@cam.ac.uk

Abstract

Chronic use of amphetamines and/or opiates has been associated with a wide range of cognitive deficits, involving domains of attention, inhibitory control, planning, decision-making, learning and memory. Although both amphetamine and opiate users show marked impairment in various aspects of cognitive function, the impairment profile is distinctly different according to the substance of abuse. In light of evidence showing that cognitive impairment in drug users has a negative impact on treatment engagement and efficacy, we review substance-specific deficits on executive and memory function, and discuss possibilities to address these during treatment intervention.

PMID:
17690986
PMCID:
PMC3639428
DOI:
10.1007/s11065-007-9033-y
[Indexed for MEDLINE]
Free PMC Article
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