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J Stroke Cerebrovasc Dis. 2007 Jan-Feb;16(1):21-4.

Predictors for recanalization after intravenous thrombolysis in acute ischemic stroke.

Author information

1
Department of Neurology, Haukeland University Hospital, Bergen, Norway. erik.askevold@gmail.com <erik.askevold@gmail.com>

Abstract

OBJECTIVE:

The purpose of this study was to evaluate clinical aspects of recanalization and to assess variables associated with early recanalization.

METHODS:

In all, 27 consecutive patients treated with intravenous thrombolysis were examined with the National Institutes of Health Stroke Scale (NIHSS) and transcranial Doppler ultrasound at presentation and at 2 and 24 hours after treatment.

RESULTS:

Recanalization less than 24 hours after treatment was found in 70% of patients. Patients who recanalized had lower NIHSS score on presentation (P = .01) and significant improvement in NIHSS score at 0 to 2 hours (P = .042) and 0 to 24 hours (P = .002) compared with those who did not recanalize. Atrial fibrillation (P = .04), higher serum glucose values on presentation (P = .05), and more traditional risk factors (P = .05) were associated with no recanalization.

CONCLUSIONS:

Recanalization is associated with clinical improvement. High NIHSS score, atrial fibrillation, high serum glucose, and higher number of risk factors indicate a reduced probability for recanalization.

[Indexed for MEDLINE]

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