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Am J Health Promot. 2007 Jul-Aug;21(6):510-6.

The effects of an intensive lifestyle modification program on carotid artery intima-media thickness: a randomized trial.

Author information

1
College of Health and Human Performance, Brigham Young University, Provo, Utah 84602, USA. steve_aldana@byu.edu

Abstract

PURPOSE:

This study evaluated the effect of the Dr. Dean Ornish Program for Reversing Heart Disease on cardiovascular disease as measured by the intima-media thickness of the common carotid artery and compared this effect to outcomes from patients participating in traditional cardiac rehabilitation.

DESIGN:

Randomized clinical trial.

SETTING:

Swedish American Health System.

SUBJECTS:

Ninety three patients with clinically confirmed coronary artery disease were randomly assigned to the intervention (n = 46) or traditional cardiac rehabilitation (n = 47).

INTERVENTION:

Dr. Dean Ornish Program for Reversing Heart Disease.

MEASURES:

Ultrasound of the carotid artery and other cardiovascular risk factors were measured at baseline, 6, and 12 months.

ANALYSIS:

Intent-to-treat analysis.

RESULTS:

There was no significant reduction in the carotid intima-media thickness of the carotid artery in the Ornish group or the cardiac rehabilitation group. Ornish Program participants had significantly improved dietary habits (p < .001), weight (p < .001), and body mass index (p < .001) as compared with the rehabilitation group. The decrease in the number of patients with angina from baseline to 12 months was 44% in Ornish and 12% in cardiac rehabilitation.

CONCLUSIONS:

The Ornish Program appears to causes improvements in cardiovascular risk factors but does not appear to change the atherosclerotic process as it affects the carotid artery.

PMID:
17674638
DOI:
10.4278/0890-1171-21.6.510
[Indexed for MEDLINE]

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