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Korean J Radiol. 2007 Jul-Aug;8(4):351-5.

Antenatal diagnosis of iniencephaly: sonographic and MR correlation: a case report.

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Department of MRI, Mammography and BMD, Balabhai Nanavati Hospital & Research Centre, S.V. Road, Vile Parle (West), Mumbai, INDIA.


Iniencephaly is an uncommon and fatal neural tube defect involving the occiput and inion, this occurs together with rachischisis of the cervical and thoracic spine, and retroflexion of the head. We report the ultrasound (US) and magnetic resonance (MR) imaging findings of a case of iniencephaly with clubfeet and arthrogryposis. The diagnosis of iniencephaly is easy to make on ultrasound due to the typical star-gazing fetus. However, the details of the fetal brain and spinal cord may not be adequately delineated on US. We found MR imaging to be superior for depicting central nervous system abnormalities. MR imaging has evolved as an imaging modality and it is complementary to fetal US, yet US remains the screening modality of choice.

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