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Science. 1976 Apr 2;192(4234):54-6.

Human glyceraldehyde-3-phosphate dehydrogenase in man-rodent somatic cell hybrids.

Abstract

The human enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) forms heteropolymers with the rodent enzyme in man-rodent somatic cell hybrids. A gene specifying GAPDH is syntenic with the genes specifying the glycolytic enzymes triosephosphate isomerase (TPI) and lactate dehydrogenase B (LDH-B). The synteny of GAPDH, TPI, and LDH-B is the first evidence for the syntenic association of human genes that specify enzymes of the Embden-Meyerhof glycolytic pathway.

PMID:
176725
DOI:
10.1126/science.176725
[Indexed for MEDLINE]

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