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Proteins. 2007 Dec 1;69(4):699-703.

The targets of CAPRI rounds 6-12.

Author information

1
Yeast Structural Genomics, IBBMC, Université Paris-Sud, Orsay, France. joel.janin@u-psud.fr

Abstract

Six protein-protein complexes and two homodimeric proteins involved in a variety of biological processes were offered as targets to CAPRI by crystallographers in Rounds 6-12. CAPRI predictor groups had to predict their structure by docking the free proteins, which they did with a degree of success that depended largely on the amplitude of the conformation changes. In one case at least, the prediction pointed to alternative possibilities of interactions in the crystal of a complex, showing that docking methods have value even when there is an experimental structure.

PMID:
17671980
DOI:
10.1002/prot.21689
[Indexed for MEDLINE]

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