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Eur J Cancer. 2007 Oct;43(15):2203-10. Epub 2007 Jul 26.

Quality-of-life in elderly patients with cancer: a short review.

Author information

1
Internal Medicine Clinic II - Department of Haematology and Medical Oncology, Friedrich Schiller University, Erlanger Allee 101, 07747 Jena, Germany. ulrich.wedding@med.uni-jena.de

Abstract

BACKGROUND:

Prolongation of survival and maintenance or improvement of health-related quality-of-life (HRQoL) are the two important goals within the treatment of individual patients. Due to the severity of symptoms and the toxicity of treatment, HRQoL has become a major area of concern when treating cancer patients in general and elderly patients in particular.

PATIENTS AND METHODS:

We present a literature review of HRQoL aspects in elderly patients with cancer and especially address the topic whether impairments in the different tools of a comprehensive geriatric assessment (CGA) are associated with decreased HRQoL in elderly cancer patients.

RESULTS:

Elderly cancer patients tend to weight their HRQoL as more important than gain in survival, when compared to younger patients. An age-dependent decrease in different scales of HRQoL is reported in patients and normative samples. HRQoL is also a predictor of survival. The variation of HRQoL can be used in trials comparing different treatment options. In individual patients, regular measurement of HRQoL aims to improve patients-centred care. Age related impairments of different areas of CGA are associated with decreased HRQoL in elderly cancer patients.

CONCLUSIONS:

HRQoL is an important outcome with elderly cancer patients and should be assessed regularly and thoroughly.

PMID:
17662595
DOI:
10.1016/j.ejca.2007.06.001
[Indexed for MEDLINE]

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