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Diagn Microbiol Infect Dis. 2007 Sep;59(1):113-5. Epub 2007 Jul 26.

Cross-reactivity of non-Aspergillus fungal species in the Aspergillus galactomannan enzyme immunoassay.

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Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN 38103, USA.


The Aspergillus galactomannan enzyme-linked immunosorbant assay (EIA) has been demonstrated to facilitate rapid and sensitive detection of invasive aspergillosis. However, test specificity has not been fully evaluated in non-Aspergillus fungal species. Of 53 fungal isolates, cross-reactivity was observed with 5 non-Aspergillus spp.: Blastomyces dermatitidis, Nigrospora oryzae, Paecilomyces lilacinus, Penicillium chrysogenum, and Trichothecium roseum.

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