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Future Microbiol. 2007 Apr;2(2):175-85.

Recent developments and future prospects in subtyping of foodborne bacterial pathogens.

Author information

1
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. EHyytia-Trees@cdc.gov

Abstract

Infections caused by foodborne bacterial pathogens continue to be a major public health issue around the world. During the past decade, pulsed-field gel electrophoresis (PFGE) has become the gold standard for molecular subtyping and source tracking of most foodborne bacteria. Owing to problems inherent in PFGE technology, new methods have been developed focusing on DNA sequence-based subtyping. This review discusses the feasibility of using multilocus sequence typing, multiple-locus variable-number tandem repeat analysis, single nucleotide polymorphisms, microarrays, whole genome sequencing and mass spectrometry for subtyping foodborne bacterial pathogens.

PMID:
17661654
DOI:
10.2217/17460913.2.2.175
[Indexed for MEDLINE]

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