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Trans R Soc Trop Med Hyg. 2008 Mar;102(3):211-2. Epub 2007 Jul 20.

Hepatitis E: a neglected threat.

Author information

1
Department of Virology, Armed Forces Research Institute of Medical Sciences, 315/6 Rajvithi Road, Bangkok 10400, Thailand. myintk@afrims.org

Abstract

Hepatitis E, responsible for explosive waterborne outbreaks and sporadic cases of acute hepatitis in developing countries, affects predominantly young adults and has a fatality rate as high as 25% in pregnant women. No effective treatment exists for hepatitis E; however, a vaccine using a baculovirus-expressed recombinant hepatitis E capsid protein was recently studied in Nepal. In this review, the progress made in hepatitis E research and the recently concluded vaccine trial of the recombinant protein vaccine are briefly discussed.

PMID:
17658568
DOI:
10.1016/j.trstmh.2007.03.014
[Indexed for MEDLINE]
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