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J Am Acad Dermatol. 2007 Nov;57(5):819-23. Epub 2007 Jul 26.

Dietary glycemic index and glucose, insulin, insulin-like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels in patients with acne.

Author information

1
Medical Health Center, University of Gazi, Ankara, Turkey. yesimkaymak@yahoo.com

Abstract

BACKGROUND:

Several isolated observations have suggested that acne can develop in groups when a high glycemic index diet is adopted.

OBJECTIVE:

This study was designed to examine associations among daily diet glycemic index, glycemic loads, serum insulin levels, and acne.

METHODS:

A total of 49 patients with acne and 42 healthy control subjects were included in the study. At the initial visit, fasting glucose, insulin, insulin-like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels were measured. A voluntary self-completed questionnaire was administered and participants were asked how frequently they consumed the specified amount of food. Overall glycemic index and dietary glycemic load were calculated.

RESULTS:

No significant differences were observed between patients with acne and control subjects in serum glucose, insulin, leptin levels, overall glycemic index, or dietary glycemic load.

LIMITATIONS:

The information and data obtained from this questionnaire were limited to patients' own recollections.

CONCLUSION:

Results of this study indicate that dietary glycemic index, glycemic load, and insulin levels do not have a role in pathogenesis of acne in younger patients.

Comment in

PMID:
17655968
DOI:
10.1016/j.jaad.2007.06.028
[Indexed for MEDLINE]

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