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Acta Psychiatr Scand. 2007 Sep;116(3):226-32.

Yoga therapy as an add-on treatment in the management of patients with schizophrenia--a randomized controlled trial.

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Department of Psychiatry, National Institute of Mental Health and NeuroSciences, Bangalore 560029, India.



Treatment of schizophrenia has remained unsatisfactory despite the availability of antipsychotics. This study examined the efficacy of yoga therapy (YT) as an add-on treatment to the ongoing antipsychotic treatment.


Sixty-one moderately ill schizophrenia patients were randomly assigned to YT (n = 31) and physical exercise therapy (PT; n = 30) for 4 months. They were assessed at baseline and 4 months after the start of intervention, by a rater who was blind to their group status.


Forty-one subjects (YT = 21; PT = 20) were available at the end of 4 months for assessment. Subjects in the YT group had significantly less psychopathology than those in the PT group at the end of 4 months. They also had significantly greater social and occupational functioning and quality of life.


Both non-pharmacological interventions contribute to reduction in symptoms, with YT having better efficacy.

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