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Arch Gynecol Obstet. 2008 Jan;277(1):75-8. Epub 2007 Jul 25.

Good pregnancy outcome after prenatal exposure to bleomycin, etoposide and cisplatin for ovarian immature teratoma: a case report and literature review.

Author information

1
Gynecologic Oncology Department, Vali-e-Asr Hospital, Imam Khomeini Hospital Complex, Keshavarz Boulevard, Tehran, Iran. drkarimi2001@yahoo.com

Abstract

AIM:

The administration of bleomycin plus etoposide and cisplatin during pregnancy is rare.

MATERIALS AND METHODS:

We describe a case with good pregnancy outcome after exposure to these chemotherapeutic agents at the third trimester of pregnancy.

RESULTS AND DISCUSSION:

A pregnant woman with stage IIIc immature teratoma underwent surgical staging, and received two cycles of bleomycin, etoposide and cisplatin from the 29th week of pregnancy until delivery. The patient did not have any evidence of recurrence of ovarian cancer for 1.5 years. Her infant did not have any evidence of minor or major malformations, and showed normal neurological development during 1.5 years of follow-up.

PMID:
17653741
DOI:
10.1007/s00404-007-0416-3
[Indexed for MEDLINE]

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