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Clin Vaccine Immunol. 2007 Sep;14(9):1242-4. Epub 2007 Jul 25.

Quality assurance program for peripheral blood mononuclear cell cryopreservation.

Author information

1
University of Colorado Health Sciences Center, Denver, Colorado, USA. Adriana.Weinberg@uchsc.edu

Abstract

Seven Brazilian sites participating in the Pediatric AIDS Clinical Trials Group international cryopreservation quality assurance pilot program cryopreserved and shipped peripheral blood mononuclear cells (PBMC) to a central U.S. laboratory for analysis. Cell viability and recovery significantly increased over time. A wet-laboratory training session conducted at the central laboratory significantly improved the quality of the cryopreserved PBMC.

PMID:
17652524
PMCID:
PMC2043300
DOI:
10.1128/CVI.00187-07
[Indexed for MEDLINE]
Free PMC Article

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