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Proc Am Thorac Soc. 2007 Aug 1;4(4):306-9.

High-resolution computed tomography of the lung in children with cystic fibrosis: technical factors.

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Department of Radiology, Columbus Children's Hospital, Ohio State University, Columbus, Ohio 43205-2696, USA.


A standard technique that controls for respiratory motion and lung volumes during imaging is necessary if high-resolution computed tomography is to be used as an outcome measure in children with cystic fibrosis. End-inspiratory and expiratory imaging allows for the detection and differentiation of early lung disease. In children ages 0-5 years, a noninvasive controlled ventilation technique is ideal, and can be used in combination with raised-volume infant pulmonary function tests. In older children, a spirometric-assisted or spirometric-triggered technique should be used. With optimal technique, radiation dose settings (kVp and mA) can be lowered to achieve a diagnostic screening high-resolution computed tomography of the lungs at a dose equivalent to that of the chest radiograph.

[Indexed for MEDLINE]

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