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FEBS Lett. 1991 Dec 16;295(1-3):1-2.

(HX)n repeats: a pH-controlled protein-protein interaction motif of eukaryotic transcription factors?

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1
Institut für Molekularbiologie, Medizinische Hochschule Hannover, Germany.

Abstract

A characteristic sequence repeat of type His-X, repeated several times in a row, is present in several eukaryotic transcription factors, e.g. HPHAHPHP in paired protein. Detailed molecular modelling and database searches lead to the suggestion that (HX)n repeats can mediate interaction between transcription factors in a pH-controlled fashion.

PMID:
1765137
[Indexed for MEDLINE]
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