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Indian J Dermatol Venereol Leprol. 2003 Jul-Aug;69(4):271-3.

Topical lincomycin gel in acne vulgaris: a multicentric placebo controlled study.

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1
Wallace Pharmaceutical Ltd., Mumbai.

Abstract

INTRODUCTION:

Acne vulgaris is commonly treated with topical antibacterials. We evaluated lincomycin gel, a new topical formulation for mild to moderate acne.

MATERIAL AND METHODS:

A multicentric, randomized, double blind, placebo controlled, clinical trial was conducted with lincomycin hydrochloride in 2% gel form in 200 patients with grade II and grade III acne. The severity of acne lesions was noted at baseline and after 4 weeks.

RESULTS:

About 70% cases in the study group showed a good to excellent response, which was significantly more as compared to 23% in the placebo group. The frequency and severity of adverse reactions in the two groups were similar.

CONCLUSION:

Lincomycin hydrochloride gel is an effective and safe treatment option for mild to moderate acne vulgaris.

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PMID:
17642909
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